Infectious particles derived from Semliki Forest virus vectors encoding murine leukemia virus envelopes

  • Lebedeva I
  • Fujita K
  • Nihrane A
  • et al.
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Abstract

Semliki Forest virus vectors encoding murine leukemia virus (MLV) envelope protein with a truncated cytoplasmic tail generate submicrometer, cell-associated, membranous particles that transmit replication-competent vector RNA specifically to cells bearing the MLV receptor. Such "minimal" viruses could have applications as retroviral vaccines or in the study of virus evolution.

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Lebedeva, I., Fujita, K., Nihrane, A., & Silver, J. (1997). Infectious particles derived from Semliki Forest virus vectors encoding murine leukemia virus envelopes. Journal of Virology, 71(9), 7061–7067. https://doi.org/10.1128/jvi.71.9.7061-7067.1997

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