P-163VALIDATION OF BODE INDEX IN PREDICTION OF POSTOPERATIVE COMPLICATIONS AFTER PULMONARY LOBECTOMY: A PRELIMINARY STUDY

Abstract

Objectives: BODE index (B body mass index, O airflow obstruction, D dyspnoea, E exercise capacity) is a well-documented, simple grading scale predicting risk of death due to respiratory and other causes among patients with chronic obstructive pulmonary disease. The aim of the study was to validate the applicability of BODE index in predicting early morbidity after pulmonary resections. Methods: Observational data of 87 patients who underwent lobectomy due to non-small cell lung cancer were analyzed. The influence of identified BODE index value 0 (n = 53), 1 (n = 27), 2 (n = 7) on postoperative complications was evaluated. Each of the components of the BODE index scale were analyzed separately (predicted forced expiratory volume in 1 second, Medical Research Council [MMRC] dyspnoea scale, distance walked in six minutes and body mass index [BMI]). Results: Cardiac complications occurred more often in patients with higher BODE index (11.7% if BODE index exceeded 1 vs 5.6% in BODE index 0 P < 0.01). Consistently with original scale we identified higher pulmonary complications rate in patients with lower BMI (25% vs 7% P = 0.035). Complications occurred less common in patients with lower BODE index (28% BODE index 0 vs 44% BODE index 1 or more P = 0.199). On the base of the power = 0.8 and alpha level 0.05, the estimated group in which the difference could be calculated as significant is assumed for 299 patients. Higher value of MMRC dyspnoea scale was associated with higher complication rates (29% for 0 vs 48% in 1 or 2; P = 0.171). The estimated group was accounted for 258 patients to prove the significant impact. Significant difference in pulmonary complications between BODE index 0 (11%) and more (23%) would be uncovered in group of 309 patients. Conclusions: BODE index, as well as its components, could be helpful in identification of patients with higher risk of postoperative complications.