Avaliação de sóleos de ratas wistar ooforectomizadas e remobilizadas em meio aquático

Abstract

Introduction: uncertainty about the most effective way to muscles remobilization after periods of immobilization. Objective: to evaluate the behavior of swimming remobilization on histomorphometric soleus muscle parameters of ovariectomized rats. Methods: we used 24 Wistar rats divided into four groups: G1: underwent oophorectomy, immobilization for 15 days and remobilized freely; G2: oophorectomy, immobilization and remobilized with swimming for 10 days; G3: pseudo-oophorectomy, immobilization and remobilized freely; G4: pseudo-oophorectomy, immobilization and remobilized with swimming. The right and left soleus muscles were dissected for longitudinal and transverse histomorphometric analysis. The count of sarcomeres occurred at 300 μm and muscle fiber length was measured by analog caliper. The muscle weight was obtained in an analytical scale and the diameter was performed on 100 fibers per muscle. Results: there was a significant reduction in both, the longitudinal and transversal analysis, when comparing the right with the left soleus muscles of all groups. Conclusion: the immobilization of the soleus muscle of ovariectomized rats and pseudo-ovariectomized cause deleterious effects on muscle morphology and remobilization through swimming was not able to promote the return of the structural patterns of the soleus muscle.