Epithelial interleukin-8 responses to oral bacterial biofilms

Abstract

An in vitro model of bacterial biofilms on rigid gas-permeable contact lenses (RGPLs) was developed to challenge oral epithelial cells. This novel model provided seminal data on oral biofilm-host cell interactions, and with selected bacteria, the biofilms were more effective than their planktonic counterparts at stimulating host cell responses. Copyright © 2011, American Society for Microbiology. All Rights Reserved.