Will the promise of translational neuropsychopharmacology research ever deliver? The lion’s roar; the kitten’s purr

Abstract

The gap between neuropsychopharmacology research claims ( the lion’s roar ) and effective treatments for neuropsychiatric disorders ( the kitten’s purr ) persists. However, a pattern of purrs over time may be as important as a loud roar. This perspective pulls together diverse preclinical and clinical voices of major figures in the neuropsychopharmacology research field to address how inter-disciplinary scientific approaches progress from thinking about the brain and its disorders to testing novel hypotheses to implementing treatments that may improve brain health in individuals with neuropsychiatric disorders.