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Canine exfoliative cutaneous lupus erythematosus in two mixed breed littermates

Veterinary Dermatology (2025) 36(1) 99-103
DOI: 10.1111/vde.13301
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Abstract

Canine exfoliative cutaneous lupus erythematosus (ECLE) is the rarest variant of cutaneous lupus in dogs and has strong breed predilections. This report presents the clinical, histopathological and immunohistochemical features of two ECLE cases in mixed breed littermates and confirms the expected genetic mutation. A therapeutic response to oclacitinib also is documented.

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Dumitrache, M. O., Ursache, A. L., Toma, C., Negoescu, A., Rietmann, S. J., Leeb, T., & Cadiergues, M. C. (2025). Canine exfoliative cutaneous lupus erythematosus in two mixed breed littermates. Veterinary Dermatology, 36(1), 99–103. https://doi.org/10.1111/vde.13301

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