Pulmonary involvement in cryoglobulinemia usually is mild. We present a rare case of severe lung involvement in mixed cryoglobulinemia. A 73-year-old woman with cryoglobulinemic glomerulonephritis was admitted. Dyspnea appeared suddenly two days later. She received the diagnosis of acute lung injury according to the concept proposed by the American-European Consensus Conference. Management required corticosteroid pulse therapy and plasma exchange. This case is the first description of successful early and long-term management of severe lung involvement observed in cryoglobulinemia. Although she has been free of chest symptoms for seven months, further follow-up may be necessary to assess the potential danger of relapse.
CITATION STYLE
Suzuki, R., Morita, H., Komukai, D., Hasegawa, T., Nakao, N., Ideura, T., & Yoshimura, A. (2003). Mixed cryoglobulinemia due to chronic hepatitis C with severe pulmonary involvement. Internal Medicine, 42(12), 1210–1214. https://doi.org/10.2169/internalmedicine.42.1210
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