Fecal microbiota transfer for multidrug-resistant gram-negatives: A clinical success combined with microbiological failure

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Abstract

Combined fecal microbiota transfer and antibiotic treatment prevented recurrences of urinary tract infections with multidrug- resistant (MDR) Pseudomonas aeruginosa, but it failed to eradicate intestinal colonization with MDR Escherichia coli. Based on microbiota analysis, failure was not associated with distinct diminished microbiota diversity.

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Stalenhoef, J. E., Terveer, E. M., Knetsch, C. W., van’t Hof, P. J., Vlasveld, I. N., Keller, J. J., … Kuijper, E. J. (2017). Fecal microbiota transfer for multidrug-resistant gram-negatives: A clinical success combined with microbiological failure. Open Forum Infectious Diseases, 4(2). https://doi.org/10.1093/ofid/ofx047

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