From canines to humans: Clinical importance of Staphylococcus pseudintermedius

Abstract

S. pseudintermedius colonizes and infects animals and is a zoonotic pathogen. Infections in canines are primarily SSTIs, and, in many cases, dogs have predisposing factors leading to infection. Human infections are also predominantly SSTIs and often, but not always, with documented canine involvement. The invasive potential of S. pseudintermedius and its complement of virulence factors—many of which mirror those associated with S. aureus—demonstrate this organism has the potential to cause serious disease. β-lactam resistance has emerged as a serious problem for canine health and is typically associated with MDR. Therefore, given the close relationship between canines and humans, S. pseudintermedius is an important candidate for One Health initiatives.