Exercise as a candidate antitumor strategy: A window into the future

Abstract

Observational findings suggest exercise is associated with improved outcomes in early-stage breast cancer. However, whether exercise has biological activity in patients with breast cancer has not been investigated. Preoperative window of opportunity studies provide a setting in which to test the short-term effects of novel treatment strategies on validated surrogates. See related article by Ligibel et al., p. 5398.