A study of oral glucose tolerance test in preeclampsia

Abstract

Pregnancy induces a state of insulin resistance leading to disturbed carbohydrate metabolism and increased incidence of preeclampsia-eclampsia. There is increased incidence of fetal morbidity and mortality. The present study was carried out in 25 mild preeclamptic woman, 25 severe preeclamptic woman and 50 age, parity and gestation matched normotensive pregnant women. Thorough clinical examination was done and hemoglobin, urine complete examination, blood urea, serum uric acid, creatinine and oral glucose tolerance were estimated. There is significant increase in perinatal mortality and morbidity in severe preeclampsia. Hypoglycaemia was more commonly seen in severe preeclampsia and hyperglycaemia in mild preeclampsia. Hence, blood glucose estimation is important to predict the fetal outcome in such patients.