Non-Hodgkin's lymphomas: Clinical study of Waldeyer's ring and cervical lymph nodes

Abstract

Between June 1988 and December 1996, 57 patients with non-Hodgkin's lymphomas of the head and neck were treated at our department. The primary lesion was located in Waldeyer's ring in 31 patients and cervical lymph nodes in 26 patients. These patients, who were diagnosed as Stage I or II, were treated with chemotherapy and radiation. The chemotherapy regimen consisted of pirarubicin (45 mg/m2; day 1), cyclophosphamide (750 mg/m2; day1), vindesine (1.5 mg/m2; day 1) and predonisolone (100 mg/body; days 1-5). The complete and partial response rates were 79% and 82% respectively. The five-year estimated overall survival rate calculated by Kaplan-Meier method was 75%. We concluded that the combination of chemotherapy regimen (THP-CVP) and radiation were useful and safe for treating non-Hodgkin's lymphomas of the head and neck.