Neonatal Lupus Erythematosus: A Case Report and Review of the Literature

Abstract

Neonatal lupus erythematosus (NLE) is a rare autoimmune condition caused by transplacental passage of maternal IgG autoantibodies to the fetus. It often presents with erythematous annular lesions on the scalp and periorbital area that appear after exposure to sunlight. Clinicians should be aware of the broad manifestations of neonatal lupus erythematosus, including cutaneous, cardiac, hematologic, hepatic and neurological manifestations. We present a case of cutaneous neonatal lupus erythematosus with rare central nervous system findings and perform a literature review on the subject.