Association of Age and Serum Vitamin D Levels in Men with Metabolic Syndrome

Abstract

Objective: To determine the association of age and serum vitamin D levels in men with (Mets) and without (NMetS) metabolic syndromes. Study Design: Descriptive study. Place and Duration of Study: King Abdulaziz University Hospital (KAUH), Jeddah, Kingdom of Saudi Arabia (KSA), from January 2019 to December 2020. Methodology: Properly diagnosed male subjects with MetS [n: 113 (49.13%); age: 26-60 years], and age-matched control subjects with NMetS [n:117 (50.87%); age: 26-60 years] were studied for the determination of serum vitamin D (vitD) levels, and correlation of age and serum vitD. Results: Non-significant change in serum vitD levels were obtained in MetS compared to NMetS (p >0.05) for whole data; as well as in MetS compared to NMetS subjects for all age-range groups. Insufficiency of serum vitD was found in both MetS and NMets subjects. However, mean values for MetS and NMetS showed age-wise lowering in vitamin D and highly significant negative linear correlation of age and vitD for MetS (R: -0.508, p <0.001) and NMetS (R: -0.522, p <0.001). Conclusion: Present report, emphasising the significant negative linear correlation of age with serum vitD levels in MetS and NMetS subjects, provides potential information for understanding the discomforts caused by the insufficiency of vitamin D with the increase in age.