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Total Synthesis of Cyclopiamide A Using Palladium-Catalyzed Domino Cyclization

Molecules (2020) 25(21)
DOI: 10.3390/molecules25214903
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Abstract

Total synthesis of cyclopiamide A was accomplished using a palladium-catalyzed domino cyclization. Three rings in the tetracyclic skeleton of cyclopiamide A were constructed in a one-step domino reaction incorporating double carbopalladation and C-H activation.

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Park, S., Shin, K. J., & Seo, J. H. (2020). Total Synthesis of Cyclopiamide A Using Palladium-Catalyzed Domino Cyclization. Molecules, 25(21). https://doi.org/10.3390/molecules25214903

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