Telomestatin (TMS: 1) is as a potent and selective telomeric G-quadruplex binder. Two molecules of TMS were suggested to be intercalated to one telomeric G-quadruplex according to docking study. In this paper, we designed and synthesized hexaoxazole TMS derivative (6OTD) dimer, and evaluated its G-quadruplex stabilizing ability.
CITATION STYLE
Iida, K., Tera, M., Shin-Ya, K., & Nagasawa, K. (2009). G-quadruplex recognition by macrocyclic hexaoxazole (6OTD) dimer. Nucleic Acids Symposium Series (2004), (53), 233–234. https://doi.org/10.1093/nass/nrp117
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