The Current Trends in Microspheres: A Review

Abstract

The idea of targeted drug delivery is to concentrate the treatment in the target tissues while lowering the relative concentration of the drug in the non-target tissues. As a result, the medication is concentrated at the desired location. As a result, the medication has no effect on the tissues nearby. Therefore, by combining the drug with a carrier particle like microspheres, nanoparticles, liposomes, niosomes, etc. that regulates the release and absorption characteristics of the drug, carrier technology offers an intelligent way for drug delivery. Microspheres are naturally biodegradable powders made of proteins or synthetic polymers that flow freely and preferably have a particle size of less than 200 m. If improved, it is the trustworthy method for maintaining the desired concentration at the site of interest without unfavourable effects and reliably delivering the drug to the target site with specificity. Microspheres attracted a lot of interest for their sustained release as well as their ability to direct anti-cancer medications to the tumour. Microspheres will play a key role in novel drug delivery in the future by fusing together a variety of other strategies, especially in diseased cell sorting, diagnostics, gene & genetic materials, safe, targeted, and efficient in vivo delivery, and supplements as miniature representations of diseased organs and tissues in the body. Keywords: Microspheres, controlled release, Types of microspheres, Methods of preparation, characterisation of microspheres, applications.