The Challenging Role of Flavonoids as a Potential Phytochemical to Treat Anxiety

Abstract

Numerous mental diseases can be caused by anxiety or anxiety-like effects, but phobia is a prevalent overcoming symptom that frequently causes stress. At present, two primary anxiety-treatment approaches are being considered: Psychotherapy and pharmacotherapy. So many traditional synthetic anxiolytic drugs with such a variety of side effects are used in the pharmacological clinical approach. As a result, scientists are searching for studies that will help them find suitable safe medications from plant sources. large experimental studies have assured that dietary phytoconstituents such as terpenoids, alkaloids, phenolic compounds, flavonoids, lignan, saponins, and cinnamates, and plant infusion comprising a combination of the various substance, have stronger action in a variety of the anxiety models in animals. The mechanisms of action of anxiolytics involve relationships with the GABA A receptor on both non-BZD sites and in Benzodiazepine (BZD).