Homeostatic control of meiotic crossovers

  • Papatriantafyllou M
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Abstract

Crossovers form between homologous chromosomes after the generation of double-strand breaks (DSBs) and support accurate chromosome segregation during meiosis. Although DSB frequency varies among meiotic cells, the number of crossovers is tightly regulated to avoid fetal aneuploidy.

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Papatriantafyllou, M. (2012). Homeostatic control of meiotic crossovers. Nature Reviews Molecular Cell Biology, 13(4), 211–211. https://doi.org/10.1038/nrm3326

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