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The FBW7-KLF2 axis regulates endothelial functions

Cell Research (2013) 23(6) 741-743
DOI: 10.1038/cr.2013.50
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Abstract

FBW7 tumor suppressor suppresses the growth and survival of tumor cells by promoting the degradation of several oncoproteins, and induces endothelial differentiation by modulating the NF1/RAS axis. A recent study in this issue of Cell Research showed that FBW7 further regulates endothelial functions via degrading transcription factor KLF2. © 2013 IBCB, SIBS, CAS All rights reserved.

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Zhao, Y., & Sun, Y. (2013). The FBW7-KLF2 axis regulates endothelial functions. Cell Research, 23(6), 741–743. https://doi.org/10.1038/cr.2013.50

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