A 4% erythromycin and zinc combination (Zineryt®) versus 2% erythromycin (Eryderm®) in acne vulgaris: a randomized, double‐blind comparative study

Abstract

A double‐blind, randomized multi‐centre study was performed to evaluate the efficacy of a 4% erythromycin and zinc combination (Zineryt®) versus 2% erythromycin (Eryderm®). One‐hundred and twenty‐two patients suffering from acne vulgaris were treated with either Zineryt® lotion or 2% erythromycin lotion. Acne grading and lesion counts for comedones, papules, pustules, nodules and macules were performed at each visit at 0, 1, 2, 4, 8 and 12 weeks. Treatment with Zineryt® lotion was found to be more effective than with 2% erythromycin as regards the reduction in number of the acne lesions and the severity grade of the acne. Copyright © 1989, Wiley Blackwell. All rights reserved