Optimal Population Coding for Dynamic Input by Nonequilibrium Networks

Abstract

The efficient coding hypothesis states that neural response should maximize its information about the external input. Theoretical studies focus on optimal response in single neuron and population code in networks with weak pairwise interactions. However, more biological settings with asymmetric connectivity and the encoding for dynamical stimuli have not been well-characterized. Here, we study the collective response in a kinetic Ising model that encodes the dynamic input. We apply gradient-based method and mean-field approximation to reconstruct networks given the neural code that encodes dynamic input patterns. We measure network asymmetry, decoding performance, and entropy production from networks that generate optimal population code. We analyze how stimulus correlation, time scale, and reliability of the network affect optimal encoding networks. Specifically, we find network dynamics altered by statistics of the dynamic input, identify stimulus encoding strategies, and show optimal effective temperature in the asymmetric networks. We further discuss how this approach connects to the Bayesian framework and continuous recurrent neural networks. Together, these results bridge concepts of nonequilibrium physics with the analyses of dynamics and coding in networks.