Neighbouring group participation by amide N-H and its possible biological significance

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Abstract

The titled phenomenon is possibly indicated in the hydrolysis of 4-(1-aziridin-1-ylmethanoyl)-5H-phenanthridin-6-one (7b); the relay version is believed to occur in organised polypeptides.

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Chandrasekhar, S., & Srinivasa Gopalan, S. (2000). Neighbouring group participation by amide N-H and its possible biological significance. Journal of Chemical Research - Part S, (11), 504–505. https://doi.org/10.3184/030823400103166111

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