Synthesis of amidoalkyl naphthol via Ritter-type reaction catalysed by heteropolyanion-based ionic liquid

Abstract

A facile and efficient procedure for the preparation of amidoalkyl naphthols via a Ritter-type reaction of 2-naphthol, aromatic aldehydes and amide in the presence of heteropolyanion-based functionalized ionic liquid has been described. The one-pot solvent-free three-component reaction is accomplished at 110 C for 5-10 min in reasonable to good yield ranging from 73% to 94%. The catalyst could be recovered and reused at least six times without noticeably decreasing the catalytic activity. [Figure not available: see fulltext.] © 2013 Indian Academy of Sciences.