Study of the impact of consanguinity on abortion and mortality in the population of Beni Abbes (southwestern Algeria)

Abstract

Background: Despite the numerous studies confirming the involvement of consanguinity in health problems, some populations around the world continue to practice this marital behavior. Algeria, like many Arab-Muslim countries, has very high consanguinity rates that require studies to measure the effects on public health. This study aims to estimate the frequency of consanguinity and to analyze its effects on two health indicators, namely abortion, neonatal, and postnatal mortality, and it focused on the population of Beni Abbes in southwestern Algeria previously known to be a genetic isolate. Results: The results of the study revealed a high consanguinity rate of 55.06% with a clear preference of first cousin marriages. A highly significant correlation was highlighted between inbreeding and the incidence of abortion as well as post and neonatal mortality. Conclusion: These results are an encouraging indicator for further future genetic studies on this population, especially since this locality is likely to remain a genetic isolate. In order to reduce the adverse health effects of consanguinity, it is essential to establish genetic counseling services in health facilities and to promote the dissemination of information on risks arising from consanguineous marriages through health education for populations.