Metabolic syndrome and gender differences in postprandial lipaemia

Abstract

Postprandial hyperlipidaemia may be a predictor of vascular risk. We evaluated postprandial lipaemia after an oral fat tolerance test (OFTT) in men (n = 41) and women (n = 21) with metabolic syndrome (MetS). Triglyceride (TG) levels were measured before and 2, 4, 6 and 8 h after the fat load. Men showed a greater plasma TG response 8 h after the fat load (284 ± 117 versus 224 ± 126 mg/dl, P = 0.029). Only fasting TG levels significantly predicted the TG area under the curve (AUC) and incremental AUC. Men had a more pronounced postprandial hypertriglyceridaemia and seem to have delayed TG clearance. © 2006, European Society of Cardiology. All rights reserved.