Chemical and in vitro anti-inflammatory assessment of Echinops erinaceus

Abstract

Echinops erinaceus Kit Tan is a wild plant growing in the middle regions of Saudi Arabia. From the available literature, nothing has been reported on its chemical analysis or biological activity. In this study, various extracts of Echinops erinaceus were estimated for their total phenolics, and flavonoids contents. The extracts were also evaluated for their in vitro antioxidant activity using DPPH, FRAP, and ABTS assays. Furthermore, the enzyme inhibitory activity against cyclooxygenases and 15-lipoxygenase was performed. The results showed that the polar and semi-polar extracts demonstrated considerable in vitro anti-inflammatory and antioxidant activities.