Phytochemical and pharmacological studies of Dalbergia sissoo growing in Egypt

Abstract

The isoflavones irisolidone, biochanin-A, muningin, tectorigenin, prunetin,genestein, sissotrin and prunetin-4-O-galactoside, the flavone nor-artocarpotin, and β-amyrin, β-sitosterol and stigmasterol were isolated and identified friom the green branches of aerial parts of Dalbergia sissoo Roxb, using silica gel column chromatography and spectral analysis. Also, 13 fatty acids were identified. The alcohol extract of the green branches of aerial parts showed a dose-dependent inhibitory effect on the motility of isolated rabbit duodenum, pronounced bronchodilation, as well as significant anti-inflammatory, antipyretic, analgesic, and estrogen-like activities. The plant extract was well tolerated by rats.