The Wae to repair: prostaglandin E2 (PGE 2 ) triggers intestinal wound repair

Abstract

Accurate wound repair is a crucial step to protect organisms from environmental damage, for example infection and toxin exposure. In this issue of The EMBO Jour- nal, Miyoshi et al (2016) have elucidated a new mechanism underpinning this process within the intestine where mesenchymal prostaglandin E2 produced following damage drives intestinal regeneration.