Journal ArticleOPEN ACCESS

Overexpression of Erg11p by the regulatable GAL1 promoter confers fluconazole resistance in Saccharomyces cerevisiae

Antimicrobial Agents and Chemotherapy (1999) 43(11) 2798-2800
DOI: 10.1128/aac.43.11.2798
51Citations
Citations of this article
47Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

The contribution of the dosage of target enzyme P-450 14α-demethylase (14αDM) to fluconazole resistance in both Candida albicans and Saccharomyces cerevisiae remains unclear. Here, we show that overexpression of Saccharomyces P-450 14αDM in S. cerevisiae, under the control of the regulatable promoter GAL1, results in azole resistance.

Cite

CITATION STYLE

APA

Kontoyiannis, D. P., Sagar, N., & Hirschi, K. D. (1999). Overexpression of Erg11p by the regulatable GAL1 promoter confers fluconazole resistance in Saccharomyces cerevisiae. Antimicrobial Agents and Chemotherapy, 43(11), 2798–2800. https://doi.org/10.1128/aac.43.11.2798

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free