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Dillapiol and apiol as specific inhibitors of the biosynthesis of aflatoxin G1 in Aspergillus parasiticus

Bioscience, Biotechnology and Biochemistry (2007) 71(9) 2329-2332
DOI: 10.1271/bbb.70264
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Abstract

Dillapiol was isolated from the essential oil of dill as a specific inhibitor of aflatoxin G1 production. It inhibited aflatoxin G 1 production by Aspergillus parasiticus with an IC50 value of 0.15 μM without inhibiting aflatoxin B1 production or fungal growth. Apiol and myristicin, congeners of dillapiol, showed similar activity with IC50 values of 0.24 and 3.5 μM, respectively.

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Razzaghi-Abyaneh, M., Yoshinari, T., Shams-Ghahfarokhi, M., Rezaee, M. B., Nagasawa, H., & Sakuda, S. (2007). Dillapiol and apiol as specific inhibitors of the biosynthesis of aflatoxin G1 in Aspergillus parasiticus. Bioscience, Biotechnology and Biochemistry, 71(9), 2329–2332. https://doi.org/10.1271/bbb.70264

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