Perioperative Dextromethorphan as an Adjunct for Postoperative Pain

  • King M
  • Ladha K
  • Gelineau A
  • et al.
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Abstract

This meta-analysis identified 21 studies describing the effects of dextromethorphan on postoperative pain and opioid consumption. Dextromethorphan was found to reduce pain from 1 to 24 h postoperatively and was found to reduce morphine requirements 24 to 48 h after surgery.

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King, M. R., Ladha, K. S., Gelineau, A. M., & Anderson, T. A. (2016). Perioperative Dextromethorphan as an Adjunct for Postoperative Pain. Anesthesiology, 124(3), 696–705. https://doi.org/10.1097/aln.0000000000000950

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