Facile deoxygenation of hydroxylated flavonoids by palladium-catalysed reduction of its triflate derivatives

Abstract

An efficient procedure to deoxygenate hydroxy substituted flavonoids, isoflavonoids and related compounds via their trifluoromethanesulfonates is presented. Their reduction with formic acid in the presence of a catalytic amount of palladium acetate, triethylamine and 1,3-bis(diphenyl-phosphanyl) propane (dppp) in DMF results in their des-hyaroxy derivatives without affecting other functional groups. © 2005 Verlag der Zeitschrift für Naturforschung.