Highly efficient ruthenium-catalyzed oxime to amide rearrangement

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Abstract

A wide range of aldoximes has been converted into the corresponding amides using the ruthenium-based catalyst Ru(PPh3)3(CO)H 2/dppe/ TsOH. The amides are generated in high yield and selectivity, with catalyst loading as low as 0.04 mol %. © 2007 American Chemical Society.

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Owston, N. A., Parker, A. J., & Williams, J. M. J. (2007). Highly efficient ruthenium-catalyzed oxime to amide rearrangement. Organic Letters, 9(18), 3599–3601. https://doi.org/10.1021/ol701445n

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