Evaluasi Karakteristik Antibakteri Ekstrak Heksan Kulit Batang Drimys piperita Hook f. terhadap Pertumbuhan Bakteri Patogenik dalam Medium Padat

Abstract

Curcuma mangga is one of the traditional medicines that have the effect dealing with infertility problems. Staphylococcus aureus and Escherichia coli are bacteria often found as the cause of the female reproductive tract infection. This study aimed to determine the antibacterial activities of several solvents of C. mangga extract against S.aureus and E.coli. C. mangga rhizome was extracted by a maceration method using ethanol (polar), chloroform (semi-polar), and n-hexane (non-polar) solvents. The antibacterial activity test against S.aureus and E.coli using Kirby Bauer with the extract various concentrations of (%) 50, 25,12.5, 6.25, 3.13, 1.56, 0.78, and 0.39. The highest inhibition zone diameter for S.aureus was obtained by ethanol (10.11 m), chloroform (9.21 mm), n-hexane (6.05 mm) extract while for E. coli, the highest inhibition zone diameter was respectively achieved by ethanol extract (8.06 mm), n-hexane (5.88 mm) and, chloroform (4.19 mm). The MIC value of ethanol extract to S. aureus was found at concentrations of 3.13% and MBC at 6.25%. The MIC value of ethanol extract on E. coli was attained at concentration of 6.25% and MBC at 12.50%. Ethanol extract of C. mangga rhizome produced the most antibacterial activities than chloroform and n-hexane.