Testicular Torsion, Antisperm Antibodies, and Clinical Repercussions

Abstract

Testicular torsion is a condition that directly affects the quality of the sperm of patients due to rupture of the blood-testis barrier; it leads to the formation of antisperm antibodies and can even affect the contralateral testis. This condition has been demonstrated previously, and multiple studies have been conducted in both animal and human models. In this review, the evidence from studies of testicular torsion, the formation of antisperm antibodies, and the clinical repercussions, mainly with respect to fertility, is presented.