Biological markers of sepsis

Abstract

Currently, the issues of early sepsis diagnosis, assessment of the effectiveness of therapies conducted, and disease prognosis are extremely relevant. In the case of sepsis, timely medical assistance is complicated by the ambiguity of symptoms and the absence of a specific diagnostic test. Therefore, the search for sepsis biomarkers with diagnostic, prognostic, and therapeutic potential is underway in medical centers worldwide. This review summarizes research results regarding the diagnostic values of sepsis biomarkers – their sensitivity, specificity, and prognostic value – as presented in scientific publications indexed in international databases.