A novel one-pot synthesis of flavones

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Abstract

In this paper, a one-pot facile route for the BiCl3/RuCl3-mediated synthesis of functionalized flavones is described, including: (i) intermolecularortho-acylation of substituted phenols with cinnamoyl chlorides, and (ii) intramolecular cyclodehydrogenation of the resultingo-hydroxychalcones. The reaction conditions are discussed herein.

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Chang, M. Y., Tsai, M. C., & Lin, C. Y. (2021). A novel one-pot synthesis of flavones. RSC Advances, 11(19), 11655–11662. https://doi.org/10.1039/d1ra00534k

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