Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), was declared a pandemic by the World Health Organization in March 2020. Severe COVID-19 cases develop severe acute respiratory syndrome, which can result in multiple organ failure, sepsis, and death. The higher risk group includes the elderly and subjects with pre-existing chronic illnesses such as obesity, hypertension, and diabetes. To date, no specific treatment or vaccine is available for COVID-19. Among many compounds, naringenin (NAR) a flavonoid present in citrus fruits has been investigated for antiviral and anti-inflammatory properties like reducing viral replication and cytokine production. In this perspective, we summarize NAR potential anti-inflammatory role in COVID-19 associated risk factors and SARS-CoV-2 infection.
CITATION STYLE
Alberca, R. W., Teixeira, F. M. E., Beserra, D. R., de Oliveira, E. A., Andrade, M. M. de S., Pietrobon, A. J., & Sato, M. N. (2020). Perspective: The Potential Effects of Naringenin in COVID-19. Frontiers in Immunology, 11. https://doi.org/10.3389/fimmu.2020.570919
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