The effect of the duration of intravenous zolendronate medication on the success of non-surgical endodontic therapy: A retrospective study

Abstract

Background: Aim of this study is to compare the clinical and radiographic success of non-surgical endodontic therapy in patients receiving intravenous zolendronate less than 1year and more than 1year. Methods: The clinical and radiographic follow-up data of 24 patients who were receiving IV zolendronate with 37 teeth were retrieved from the archives to evaluate clinical and radiographic healing at the end of 12months after non-surgical endodontic therapy. The clinical and radiographic scores of teeth treated with non-surgical endodontic therapy were analyzed. Results: The amount of non-healed and incomplete healed teeth in patients receiving zolendronate more than 1year were more than the amount of teeth of non-healed and incomplete healed in patients receiving bisphosphonates less than 1year (p < 0.05). Conclusions: There was a strong relationship between the duration of the bisphosphonate medication and endodontic success.