Correction to: A multi-ancestry genetic study of pain intensity in 598,339 veterans (Nature Medicine, (2024), 30, 4, (1075-1084), 10.1038/s41591-024-02839-5)

Abstract

Correction to: Nature Medicinehttps://doi.org/10.1038/s41591-024-02839-5, published online 1 March 2024 In the version of the article initially published, the pipeline for the cross-ancestry meta-analysis did not accurately code some SNPs such that they were not combined despite being the same polymorphism. To fix this, we correctly annotated the rsIDs for the summary statistics from each ancestry and meta-analyzed them based on the unique rsID for each polymorphism. We also corrected all downstream analyses that used the cross-ancestry meta-analysis data. Table 1 is a summary of the major changes which have been made to the main text and Fig. 1. (Table presented.) Previous analyses (n) Current analyses (n) Autosomal SNPs included in meta-analyses 16,254,110 15,895,579 Genome-wide significant variants 4,416 4,364 Linkage disequilibrium clumped index variants 158 162 Independent loci 126 125 New pain loci 69 66 Exonic variants 5 4 Pleiotropic loci with immune traits 25 23 Gene-set analyses Catecholamine uptake and startle response Dopaminergic synaptic transmission and aryl hydrocarbon receptor complex None of these changes changed any of our downstream analyses. These corrections have been made to the HTML and PDF versions of the article.