Scanning electron microscopy of acantholysis in pemphigus foliaceus

Abstract

We performed scanning electron microscopy of an inverted blister roof in a case of pemphigus foli-aceus. The loss of intercellular adherence could be easily seen with low magnification. The acantholytic ker-atinocytes displayed an irregular and sometimes polygonal contour. Round cells, typically seen in light microscopy, were also observed. The examination of a blister roof allows ultrastructural documentation of the acantholytic changes. © 2013 by Anais Brasileiros de Dermatologia.