ConSSeq: A web-based application for analysis of amino acid conservation based on HSSP database and within context of structure

Abstract

A web-based application to analyze protein amino acids conservation - Consensus Sequence (ConSSeq) is presented. ConSSeq graphically represents information about amino acid conservation based on sequence alignments reported in homology-derived structures of proteins. Beyond the relative entropy for each position in the alignment, ConSSeq also presents the consensus sequence and information about the amino acids, which are predominant at each position of the alignment. ConSSeq is part of the STING Millennium Suite and is implemented as a Java Applet. © Oxford University Press 2004; all rights reserved.