Parámetros de calcio y fósforo y su asociación con la parathormona sérica en pacientes renales crónicos en hemodiálisis

Abstract

The objective of this study was to investigate the association between calcium and phosphorus parameters with serum parathormone concentrations in patients with Chronic Kidney Disease (CKD) undergoing hemodialysis. It is descriptive quantitative cross-sectional study. The sample was composed of 50 individuals distributed in: group with up to 5 years of hemodialysis and group with more than 5 years of hemodialysis. Food consumption was assessed using 24-hour dietary recall. Descriptive analysis of quantitative variables was presented as mean and standard deviation. Data analysis was performed using the SPSS program; Student “T” test, Fisher’s exact test and Pearson’s chi-square test were used, with significance level p <0.05. The groups presented adequate serum calcium concentrations and high concentrations of phosphorus and parathormone. Patients with more than 5 years of hemodialysis had a statistically higher serum parathormone level (p= 0.034); there was an association between longer hemodialysis time and higher serum phosphorus concentrations (p= 0.039). There was a moderate positive correlation between serum parathormone and phosphorus in the group with up to 5 years of hemodialysis (p= 0.012). It was concluded that the progression of CKD increases serum phosphorus and parathormone concentrations, reflecting the pathophysiological events and altered metabolic demand inherent to the pathology.