Multimodality approach to treatment of rhinosinusal tumours

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Abstract

The treatmentdecision for rhinosinusal tumours requires accurate knowledge of the therapeutic principles specific to each histological type and tumoral extension. Therapy strategies have been developed based on the pathophysiological knowledge and the history of these tumors. Postoperative assessment remains necessary, to establish patient-specific oncological management. The purpose of this study is the retrospective analysis of cases with rhinosinusalmalignancies, diagnosed and treated in the Otolaryngology Unit of the Spiridon Emergency Clinical Hospital in Iasi. We evaluated the characteristics of the patient group using a statistical analysis that highlights the therapeutical modalities used in multimodal treatment, surgical techniques, chemotherapy, radiotherapy, and the therapeutic protocols, all of these beeing adapted to each patient so that, their effectiveness to be maximal. Rinosinusal tumours show particular elements of severity through late diagnosis due to lack of symptomatology, thus limiting the therapeutic means and their curative potential.In order to ensure a correct and complete treatment of this disease, an interdisciplinary collaboration between the ENT surgeon, ophthalmologist, neurosurgeon, imagist, oncotherapist, anatomopathologist, OMF surgeon both preoperatively in the setting of a therapeutic and postoperative strategy is absolutely necessary.Surgery has its well-established place in multimodality complex treatment whether it is curative or palliative.

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Palade, O. D., Anghelina, F., Dabija, M. G., Hainarosie, R., Domuta, E. M., Hinganu, D., … Radeanu, D. (2019). Multimodality approach to treatment of rhinosinusal tumours. Revista de Chimie, 70(5), 1848–1851. https://doi.org/10.37358/rc.19.5.7229

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