Antihyperglycemic and Hypolipidemic Potential of Kepok Banana Peel in Diabetic Rats

Abstract

The prevalence of Diabetes Mellitus (DM) is still high. DM can cause changes in lipid profiles such as hypercholesterolemia, hypertriglyceridemia, and increased LDL levels. This study aimed to test the ability of kapok banana peel extract in reducing glucose, triglyceride, and LDL cholesterol levels in streptozotocine-induced Rattus norvegicus. This type of research is an experimental design with pre and post-test control design. Twenty-five male subjects were Rattus norvegicus. Data were analyzed by the Wilcoxon test, Kruskal Wallis test, and Mann Whitney test. The length of the study was 21 days. The results of the analysis of the use of banana peel extract can reduce levels of glucose, triglycerides, and LDL cholesterol (p= 0.025, p = 0.043, p=0.043). Kepok banana peel extract has the potential as antihyperglycemic and antilipidemic in diabetic rats.