Evaluation of a new commercially available immunoglobulin M capture enzyme-linked immunosorbent assay for diagnosis of dengue virus infection

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Abstract

We evaluated the FDA-cleared InBios dengue virus (DENV) IgM capture enzyme-linked immunosorbent assay (ELISA) for qualitative detection of anti-DENV IgM antibodies from 79 serum samples obtained from dengue virus-infected patients or suspected dengue cases. The agreement, sensitivity, and specificity of the InBios assay compared to the gold standard in-house DENV IgM capture ELISA were 94, 92, and 94%, respectively. We conclude that the InBios DENV IgM capture ELISA can be effectively used for rapid diagnosis of acute or recent DENV infection. Copyright © 2013, American Society for Microbiology. All Rights Reserved.

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Namekar, M., Ellis, E. M., O’Connell, M., Elm, J., Gurary, A., Park, S. Y., … Nerurkar, V. R. (2013). Evaluation of a new commercially available immunoglobulin M capture enzyme-linked immunosorbent assay for diagnosis of dengue virus infection. Journal of Clinical Microbiology, 51(9), 3102–3106. https://doi.org/10.1128/JCM.00351-13

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