Amino-terminal sequence analysis of the Coccidioides immitis chitinase/immunodiffusion-complement fixation protein

Abstract

A chitinase isolated from Coccidioides immitis was subjected to amino- terminal protein sequence analysis. The resulting 18-amino-acid sequence was compared with the previously reported amino acid sequence of coccidioidal immunodiffusion-complement fixation (IDCF) antigen. From the homology of the two sequences, the results support the identification of the IDCF antigen with a chitinase.