Synthesis and antimicrobial evaluation of some new 2-(5,6-dihydro-4H -1,2,4-triazolo[4,3-a]benz[F]azepin-1-yl)methyl-4-substituted phthalazin-1(2H )-ones

Abstract

Starting from 4-substituted-phthalazin-1(2H)-one (1), A series of new 2-(5,6-dihydro-4H-1,2,4-triazolo[4,3-a]benz[f]azepin-1-yl)methyl)-4-substituted phthalazin-1(2H)-ones derivatives ( 5) have been synthesized. The structure of synthesized new compounds was established by spectral data and screened for their antimicrobial activities against various bacteria and fungi strains.