Quantitative comparison of two cortical surface extraction methods using MRI phantoms

Abstract

In the last decade several methods for extracting the human cerebral cortex from magnetic resonance images have been proposed. Studies comparing these methods have been few. In this study we compare a recent cortical extraction method with FreeSurfer, which has been widespread in the scientific community during recent years. The comparison is performed using realistic phantoms generated from surfaces extracted from original brain scans. The geometrical accuracy of the reconstructed surfaces is compared to the surfaces extracted from the original scan. We found that our method is comparable with FreeSurfer in terms of accuracy, and in some cases it performs better. In terms of speed our method is more than 25 times faster. © Springer-Verlag Berlin Heidelberg 2007.